Forskel mellem versioner af "Drug fever"
Spring til navigation
Spring til søgning
Admin (diskussion | bidrag) (→Lægemiddelinduceret feber (drug fever)) |
Admin (diskussion | bidrag) |
||
| Linje 15: | Linje 15: | ||
*isoniazid | *isoniazid | ||
*prokainamid | *prokainamid | ||
| + | |||
| + | '''Drug-induced fever''' is a state wherein the administration of [[Medication|drugs]] intended to help a patient causes a fever. The drug may interfere with heat dissipation peripherally, increase the rate of [[metabolism]], evoke a cellular or humoral [[immune response]], mimic endogenous [[Pyrogen (fever)|pyrogen]], or damage tissues. | ||
| + | |||
| + | ==Triggers== | ||
| + | * Directly caused by the drug,'' e.g.'' [[lamictal]], [[progesterone]], or [[chemotherapeutics]] causing [[tumor]] [[necrosis]] | ||
| + | * Possible side effect of stimulants and entactogens (e.g. [[MDMA]], [[methamphetamine]], [[PMA]], [[4-MTA]]) | ||
| + | * As an adverse reaction to drugs, ''e.g.'' [[antibiotic]]s or [[Sulfonamide (medicine)|sulfa drug]]s. | ||
| + | * After drug discontinuation, ''e.g.'' [[heroin]] or [[fentanyl]] withdrawal | ||
| + | * [[Neuroleptic Malignant Syndrome]]; rare, life-threatening hyperpyrexia caused by antidopaminergic drugs (mostly antipsychotics) | ||
| + | * [[Serotonin Syndrome]]; excessive serotonergic activity due usually to combined use of serotonergic drugs (e.g. [[antidepressants]], [[stimulants]], [[triptans]]) | ||
| + | * [[5HT2A]] [[agonists]], ''e.g.'' [[psilocybin]] or [[LSD]] | ||
| + | |||
| + | ==External links== | ||
| + | [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3522163&dopt=Abstract Drug Induced Fever information at PubMed] | ||
| + | |||
| + | [[Category:Medical terms]] | ||
| + | |||
| + | {{medicine-stub}} | ||
| + | {{General symptoms and signs}} | ||
Versionen fra 17. apr 2010, 02:30
Lægemiddelinduceret feber (drug fever)
Bør altid overvejes ved uklare febertilstande. Vedvarende feber + C-reaktivt protein (CRP) i lavt område tyder på drug-fever.
Patienten får almindeligvis feber 3-5 dage efter påbegyndt behandling, men feberen kan af og til komme senere
Aktuelle medikamenter er:
- penicilliner
- cefalosporiner
- fenytoin
- salicylater
- sulfonamider
- allopurinol
- antihistaminer
- cimetidin
- isoniazid
- prokainamid
Drug-induced fever is a state wherein the administration of drugs intended to help a patient causes a fever. The drug may interfere with heat dissipation peripherally, increase the rate of metabolism, evoke a cellular or humoral immune response, mimic endogenous pyrogen, or damage tissues.
Triggers
- Directly caused by the drug, e.g. lamictal, progesterone, or chemotherapeutics causing tumor necrosis
- Possible side effect of stimulants and entactogens (e.g. MDMA, methamphetamine, PMA, 4-MTA)
- As an adverse reaction to drugs, e.g. antibiotics or sulfa drugs.
- After drug discontinuation, e.g. heroin or fentanyl withdrawal
- Neuroleptic Malignant Syndrome; rare, life-threatening hyperpyrexia caused by antidopaminergic drugs (mostly antipsychotics)
- Serotonin Syndrome; excessive serotonergic activity due usually to combined use of serotonergic drugs (e.g. antidepressants, stimulants, triptans)
- 5HT2A agonists, e.g. psilocybin or LSD
