Forskel mellem versioner af "Drug fever"
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| − | '''Drug-induced fever''' is a state wherein the administration of | + | ==Wikipedia.org== |
| + | '''Drug-induced fever''' is a state wherein the administration of drugs intended to help a patient causes a fever. The drug may interfere with heat dissipation peripherally, increase the rate of metabolism, evoke a cellular or humoral immune response, mimic endogenous pyrogen, or damage tissues. | ||
==Triggers== | ==Triggers== | ||
| − | * Directly caused by the drug,'' e.g.'' | + | * Directly caused by the drug,'' e.g.'' lamictal, progesterone, or chemotherapeutics causing tumor necrosis |
| − | * Possible side effect of stimulants and entactogens (e.g. | + | * Possible side effect of stimulants and entactogens (e.g. MDMA, methamphetamine, PMA, 4-MTA) |
| − | * As an adverse reaction to drugs, ''e.g.'' | + | * As an adverse reaction to drugs, ''e.g.'' antibiotics or sulfa drugs. |
| − | * After drug discontinuation, ''e.g.'' | + | * After drug discontinuation, ''e.g.'' heroin or fentanyl withdrawal |
| − | * | + | * Neuroleptic Malignant Syndrome; rare, life-threatening hyperpyrexia caused by antidopaminergic drugs (mostly antipsychotics) |
| − | * | + | * Serotonin Syndrome; excessive serotonergic activity due usually to combined use of serotonergic drugs (e.g. antidepressants, stimulants, triptans) |
| − | * | + | * 5HT2A agonists, ''e.g.'' psilocybin or LSD |
==External links== | ==External links== | ||
[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3522163&dopt=Abstract Drug Induced Fever information at PubMed] | [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3522163&dopt=Abstract Drug Induced Fever information at PubMed] | ||
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Versionen fra 17. apr 2010, 02:33
Indholdsfortegnelse
Lægemiddelinduceret feber (drug fever)
Bør altid overvejes ved uklare febertilstande. Vedvarende feber + C-reaktivt protein (CRP) i lavt område tyder på drug-fever.
Patienten får almindeligvis feber 3-5 dage efter påbegyndt behandling, men feberen kan af og til komme senere
Aktuelle medikamenter er:
- penicilliner
- cefalosporiner
- fenytoin
- salicylater
- sulfonamider
- allopurinol
- antihistaminer
- cimetidin
- isoniazid
- prokainamid
Wikipedia.org
Drug-induced fever is a state wherein the administration of drugs intended to help a patient causes a fever. The drug may interfere with heat dissipation peripherally, increase the rate of metabolism, evoke a cellular or humoral immune response, mimic endogenous pyrogen, or damage tissues.
Triggers
- Directly caused by the drug, e.g. lamictal, progesterone, or chemotherapeutics causing tumor necrosis
- Possible side effect of stimulants and entactogens (e.g. MDMA, methamphetamine, PMA, 4-MTA)
- As an adverse reaction to drugs, e.g. antibiotics or sulfa drugs.
- After drug discontinuation, e.g. heroin or fentanyl withdrawal
- Neuroleptic Malignant Syndrome; rare, life-threatening hyperpyrexia caused by antidopaminergic drugs (mostly antipsychotics)
- Serotonin Syndrome; excessive serotonergic activity due usually to combined use of serotonergic drugs (e.g. antidepressants, stimulants, triptans)
- 5HT2A agonists, e.g. psilocybin or LSD
